His career has him played for international football clubs and some Argentine football clubs based in his home country, Argentina.
The 38 year old football star who plays for his present football club, Club Atletico River Plate is going to retire in his present football club which is based in Argentina.
Read his retirement speech below; "Today I bid farewell to the Argentina national team, filled with immense pride for having represented my country.
Titles will always be part of history, but the love for these colours will last forever.
"Thank you, Argentina. Thank you for allowing me to fulfill my dream of becoming a world champion and wearing the most beautiful shirt in the world."
The legendary defender retires as Argentina's fifth-most capped player of all time with 139 appearances, behind only Lionel Messi, Javier Mascherano, Ángel Di María and Javier Zanetti.
Otamendi ends his international career as a World Cup winner, World Cup runner-up, two-time Copa América champion and Finalissima winner, having played in every final under Lionel Scaloni."